Correlation of red cell distribution width with the parameters of severity of kidney disease in patients undergoing hemodialysis
Introduction and Aim: The Red cell Distribution Width (RDW) is elucidated as a marker in measuring the variation of volume in erythrocytes. Many studies have revealed that RDW elevation is associated with the increased mortality risk in general population. We aimed to study the correlation of RDW with the parameters of severity of kidney disease in patients undergoing hemodialysis.
Materials and Methods: This is a retrospective observational study. By using G power statistical software with the power of 0.85, the sample size was calculated as 90. Inclusion criteria: This study was conducted from the medical records of patients of both sexes having kidney disease undergoing hemodialysis in Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, Melmaruvathur. The records were grouped into 3 groups based on the values of Red cell distribution width. Group I with RDW values 10-13%, Group II with RDW values 13.1-15%, Group III with RDW values more than 15%. Exclusion criteria: The records of patients undergoing haemodialysis having coronary artery diseases and iron deficiency anaemia were excluded. The clinical data that were collected are red cell distribution width, hemoglobin, serum creatinine and blood urea (pre & post dialysis).
Results: Our study proves that there was no correlation between RDW values and the parameters of severity of kidney disease.
Conclusion: This study suggests that RDW levels have no correlation with the urea, creatinine and hemoglobin of patients with kidney disease under chronic hemodialysis, but it is clinically significant.
Keywords: Red cell distribution width; hemodialysis; kidney disease.
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