Variation in interpeak latencies of auditory brainstem responses with age in male adults:An observation
Keywords:Aging, auditory brainstem responses, interpeak latencies
Introduction and Aim: Aging of the auditory pathway is a complex phenomenon consisting of changes in the auditory processing along with a significant elevation of the hearing threshold. The aim of our study was to see the variation in interpeak latencies (IPLs) of Auditory Brainstem Responses (ABRs) with advancing age in males.
Materials and Methods: It was an observational study conducted on 60 Indian male subjects aged between 20 and 80 years divided into three groups on the basis of age: Group 1: 20-40 years, Group 2: 41-60 years and Group 3: 61-80 years. Auditory threshold and ABRs were recorded and analysed for interpeak latencies (IPLs) – I-III,I-V and III-V in msec.The comparison of data between the groups was done using one – way ANOVA and Tukey Kramer multiple comparison test. The results were considered significantly different between the groups when ‘P value’ was ? 0.05.
Results: It was found that there was no significant difference in the auditory threshold and interpeak latencies (IPLs) when comparison was made between the three groups.
Conclusion: Hence we conclude thatage does not have any significant influence on neural conduction time of the auditory pathway which is represented by the IPLs in ABRs.
Moller, A.R. Neural mechanisms of BAEP. Electroencephalogr Clin Neurophysiol. 1999; 49:27-35.
Boettcher, F.A. Presbyacusis and the auditory brainstem response. J Speech Lang Hear Res. 2002; 45:1249-1261.
Liu, X.Y., Yan, D.Aging and hearing loss. J Pathol. 2007; 211:188-197.
Misra, U.K., Kalita, J. Brainstem auditory Evoked Potentials In: Misra UK, Kalita J, editors, Clinical neurophysiology. 1st ed. New Delhi: Elsevier; 2005: 267-286.
Jasper, H.H. Reports of committee on methods of clinical examination in electroencephalography. Electroencephalogr Clin Neurophysiol. 1958; 10:370-375.
Stockard, J.J., Pope-Stockard, J.E.,Sharborough, F.W. Brainstem auditory evoked potentials in neurology: methodology, interpretation and clinical application. In: Aminoff MJ, editor, Electrodiagnosis in clinical neurology. 3rd ed. New York: Churchill Livingstone. 1986: 487-503.
Pujol, R., Rebillard, G., Pael, J.L., Lenoir, M., Eybalin, M., Recasens, M. Glutamate neurotoxicity in the cochlea: a possible consequence of ischaemic or anoxic conditions occurring in ageing. Acta Otolaryngol. 1991; 476: 32-36.
Broverman, D.M., Klaiber, E.L., Kobayashi, Y., Vogal, W. Roles in activation and inhibition in sex differences in cognition abilities. Psychol Rev. 1968; 75: 23-50.
Mohammad, F.T., Gharib, K., Teimuri, H. Study of age effects on brainstem auditory evoked potential waveforms. J Med Sci. 2007; 7(8): 1362-1367.
Harinder, J. S., Ramsarup, S., Sharanjit, K. The study of age and sex related changes in the brainstem auditory evoked potential. J Clin and Diag Res. 2010;4: 3495-3499.
Rowe, M. J. Normal variability of the brainstem auditory evoked response in young and old subjects. Electroencephalogr Clin Neurophysiol. 1978; 441: 459-470.
Chu, N.S. Age related latency changes in the brainstem auditory evoked potentials. Electroencephalogr Clin Neurophysiol. 1985; 62 (6): 431-436.
Harkins, S.W. Effects of age and interstimulus Interval on the Brainstem Auditory Evoked Potential. Int J of Neuro 1980; 15 (1-2): 107-118.
Rosenhall, U., Björkman, G., Pedersen, K., Kall, A. Brain-stem auditory evoked potentials in different age groups. Electroencephalogr Clin Neurophysiol. 1985;62(6): 426-430.
Costa, P., Benna, P., Bianco, C., Ferrero, P., Bergamasco, B. Aging effects on brainstem auditory evoked potentials. Electroencephalogr Clin Neurophysiol. 1990;30(8): 495-500.
Oku, T., Hasegewa, M. The influence of aging on auditory brainstem response and electrocochleography in the elderly. ORL J OtorhinolaryngolRelat Spec. 1997;59(3):141-146.
Khatoon, M., Nighute, S., Awari, A. Brainstem auditory evoked potentials in different age groups. Int J Biomed Res. 2012;3(6):271-276.
Patel, K., Shah, C., Mehta, H., Patel, H., Dixit, G., Thakore, N. Study of interpeak latencies of waveforms of brainstem auditory evoked potentials in normal healthy persons. NationalJournal of Physiology, Pharmacy and Pharmacology 2017;7(8):831-834.
How to Cite
This work is licensed under a Creative Commons Attribution 4.0 International License.