Association of visceral adiposity index with cardiovascular risk factors among young adults
Keywords:cardiovascular risk, dyslipidemia, visceral adiposity index
Introduction and Aim: The frequent cause of mortality today is cardiovascular disease. Though dyslipidemia predicts cardiovascular risk, the possibility of risk cannot be excluded in normal lipid profile. Therefore, the study was conducted to associate visceral adiposity index (VAI) with cardiovascular risk factors among young adults.
Materials and Methods: It is a cross-sectional study in which 150 men and 150 women between the ages of 20 and 40 participated. A detailed clinical history, anthropometric measurements, fasting plasma glucose and fasting lipid profile were estimated. VAI was calculated.
Results: Mean VAI was 2.13±0.5 in men and 2.65±0.8 in women. Based on visceral adiposity index, 53% men and 61% women have a high risk of cardiovascular disease. VAI correlated positively with waist circumference, BMI, waist hip ratio, blood pressure, fasting plasma glucose, serum triglyceride, lipid ratios. VAI showed significant negative correlation with HDL cholesterol.
Conclusion: We explored the increase in cardiovascular risk among young adults. Though mean values of lipid profile and lipid ratios were within the desired range in our study, around 50% of the young adults had high risk for cardiovascular disease. Hence, VAI index can be used along with the existing lipid profile to identify those at increased cardiovascular risk.
Roth, G.A., Huffman, M.D., Moran, A.E., Feigin, V., Mensah, G.A., Naghavi, M., et al., Global and regional patterns in cardiovascular mortality from 1990 to 2013. Circulation. 2015; 132(17): 1667-1678.
Ivelina, M., Maria, M., Mariela, H.S., Veronika, P., Rumen, N, Markova, T., et al., Type and frequency of genetic variants for cardiovascular riskin patients with type 2 diabetes mellitus. Biomedicine. 2021 Sep 7;41(2):382-389.
Knowles, K.M., Paiva, L.L., Sanchez, S.E., Revilla, L., Lopez, T., Yasuda, M.B., et al., Waist circumference, body mass index, and other measures of adiposity in predicting cardiovascular disease risk among Peruvian adults. Int J Hypertens. 2011; 2011. 931402.
Sardarinia, M., Akbarpour, S., Lotfaliany, M., Bagherzadeh-Khiabani, F., Bozorgmanesh, M., Sheikholeslami, F., et al., Risk factors for incidence of cardiovascular diseases and all-cause mortality in a middle eastern population over a decade follow-up: Tehran lipid and glucose study. PLoS One. 2016; 11(12):e0167623
Niroumand, S., Khajedaluee, M., Khadem-Rezaiyan, M., Abrishami, M., Juya, M., Khodaee, G., et al., Atherogenic Index of Plasma (AIP): A marker of cardiovascular disease. Med J Islam Repub Iran. 2015;29:240.
Olamoyegun, M.A., Oluyombo, R., Asaolu, S.O. Evaluation of dyslipidemia, lipid ratios, and atherogenic index as cardiovascular risk factors among semi-urban dwellers in Nigeria. Ann Afr Med. 2016;15(4):194-199.
Jablonowska Lietz, B., Wrzosek, M., Wlodarczyk, M., Nowicka, G. New indexes of body fat distribution, visceral adiposity index, body adiposity index, waist to height ratio, and metabolic disturbances in the obese. Kardiol Pol. 2017;75(11):1185-1191.
Numan, A.M., Halim, H.F. Suitability of visceral adiposity index as a marker for cardiometabolic risks in Jordanian adults. Nutr Hosp. 2015;32(6):2701-2709.
Amato, M.C., Giordano, C., Pitrone, M., Galluzzo, A. Cut off points of the visceral adiposity index (VAI) identifying a visceral adipose dysfunction associated with cardiometabolic risk in a Caucasian Sicilian population. Lipids Health Dis. 2011;10:183.
American Diabetes Association. 1. Improving care and promoting health in populations: Standards of medical care in diabetes - 2018. Diabetes Care. 2018;41(Suppl. 1): S7–S12.
Chobanian, A.V., Bakris, G.L., Black, H.R., Cushman, W.C., Green, L.A., et al., The seventh report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. The JNC 7 Report JAMA. 2003; 289(19): 2560-2571.
Kurian, S., Manjula, V.D., Annamma, Zakariah J. A study on cardiovascular risk factor profile of medical students in a tertiary care hospital of central Kerala. NJMR. 2015;5(1):11-17.
World Health Organization (2005b) WHO STEPS Surveillance Manual: The WHO STEPwise approach to chronic disease risk factor surveillance. World Health Organization, Geneva.
Dobiasova, M. AIP: Atherogenic index of plasma as a significant predictor of cardiovascular risk: From research to practice. Vnitr. Lek. 2006;52(1):64-71.
Cai, G., Shi, G., Xue, S., Lu, W. The atherogenic index of plasma is a strong and independent predictor for coronary artery disease in the Chinese Han population. Medicine (Baltimore). 2017; 96(37):e8058.
Amato, MC., Giordano, C., Galia, M., Criscimanna, Angela., Vitabile, S., Midiri, M., et al., Visceral adiposity index: a reliable indicator of visceral fat function associated with cardiometabolic risk. Diabetes Care. 2010;33(4):920-922.
Bo, M.S., Cheah, W.L., Lwin, S., Moe, N.T., Win, T.T., Aung, M. Understanding the relationship between atherogenic index of plasma and cardiovascular disease risk factors among staff of a university in Malaysia. J NutrMetab. 2018:7027624.
Akhil, K.S., Ankit, M., Nidhi, S., Anand, K. Lifestyle associated risk factors in adolescents. Indian Journal of Pediatrics. 2006;73(10):901-906.
McKenzie, T.L., Marshall, S.J., Sallis, J.F., Conway, T.L. Leisure time physical activity in school environments: An observational study. Preventive medicine. 2000;30:70-77.
Hu, F.B., Li, T.Y., Colditz, G.A., Willett, W.C., Manson, J.E. Television watching and other sedentary behaviours in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA. 2003;289:1785-1791.
Healy, G.N., Dunstan, D.W., Salmon, J., Cerin, E., Shaw, J.E., Zimmet, P.Z., et al., Breaks in sedentary time: beneficial associations with metabolic risk. Diabetes Care. 2008;31:661-666.
Mohammad, Y.G., Karem, H.A., Omar, F.K., Lubna, T., Rawan, H., et al., Assessment of cardiovascular risk factors among university students: the gender factor. Cardiology Research. 2012;3(4):172-179.
Rajeev, G., Anoop, M., Naval, K.V., Dimple, K., Shaon, S.G., Aachu, A. Younger age of escalation of cardiovascular risk factors in Asian Indian subjects. BMC Cardiovascular Disorders. 2009;9:28.
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