Antibody responses induced by inactivated SARS-CoV-2 virus in healthcare workers at a rural hospital in Indonesia


  • Efrisca M. Br. Damanik
  • Herman P.L. Wungouw
  • Anita Lidesna Shinta Amat



COVID-19, immunological, health workers, vaccination


Introduction and Aim: Vaccines from various manufacturers have shown their efficacy against COVID-19 globally. In this study, the aim was to evaluate the immune response in subjects after the second vaccination with inactivated SARS-CoV-2 virus at Mamami Hospital located in a rural area in Indonesia.


Materials and Methods: The study employed a cross-sectional research design. The research took place at Mamami Hospital, Kupang City, East Nusa Tenggara, Indonesia, from April 5 to August 8, 2021. The research comprised a total of 30 health workers who served as the participants in this study.


Results: Immunoserology results show that 1 respondent was non-reactive and 2 had antibody results < 10. There were 7 respondents with antibody results > 10 - 40. Serological antibodies > 40 - 80 were found in 3 respondents. Serological antibodies > 80 - 120 were not found. Serological antibodies > 120 - 160 were found in 3 respondents. One respondent had serological antibodies ranging from 160 to 200, while 13 respondents had antibodies ranging from 200 to 400.


Conclusion: In the present study, inactivated SARS COV-2 virus vaccine significantly contributed to the acquisition of anti-SARS-CoV-2S antibodies of 30 health workers.

Author Biographies

Efrisca M. Br. Damanik

Department of Anatomical Pathology, Faculty of Medicine, and Veterinary Medicine, Universitas Nusa Cendana, Kupang, Indonesia

Herman P.L. Wungouw

Department of Radiology, Faculty of Medicine, and Veterinary Medicine, Universitas Nusa Cendana, Kupang, Indonesia

Anita Lidesna Shinta Amat

Department of Biochemistry, Faculty of Medicine, and Veterinary Medicine, Universitas Nusa Cendana, Kupang, Indonesia


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How to Cite

M. Br. Damanik E, P.L. Wungouw H, Lidesna Shinta Amat A. Antibody responses induced by inactivated SARS-CoV-2 virus in healthcare workers at a rural hospital in Indonesia. Biomedicine [Internet]. 2023 Nov. 9 [cited 2023 Dec. 2];43(5):1629-32. Available from:



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