Predictive value of insulin marker before and after recovery of Grave’s disease patients


  • Abeer Salih Ali
  • Rana Hazim Hamoode
  • Zena A. Khalaf
  • Bahaa Abdullah Lafttah Al-Rubaii



insulin, Graves disease, thyroid stimulating hormone, ; radioactive iodine 131


Introduction and Aim: Grave’s disease is a disease of the thyroid glands. Early diagnosis of hyperthyroidism can improve treatment and control. This study examined hyperthyroidism-related insulin hormone alterations before and after radioactive iodine 131 treatment. This study also examined how the medical condition affected these indicators.


Materials and Methods: The participants in this study included 50 people who were diagnosed with Grave’s disease, as well as 23 healthy individuals as controls. Direct inquiry was used as the technique for gathering demographic information from the patients who participated in the study. The thyroid stimulating and insulin hormonal levels of each patient were recorded before and after undergoing a hypothyroidism treatment regimen of three months that consisted of a dose of radioactive iodine 131 ranging from 10 to 20 mci.


Results: This research indicated a significant relation to exist between age and insulin levels among patients diagnosed with Grave’s disease. In addition, the research also demonstrated a significant association between levels of thyroid-stimulating hormone (TSH) and insulin hormones in patients both before and after radiation therapy.


Conclusion: Insulin hormonal levels could be used as a predictor of the severity of hyperthyroidism.

Author Biographies

Abeer Salih Ali

Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq

Rana Hazim Hamoode

Basic Science Department, Dentistry of College, University of Anbar, Anbar, Iraq

Zena A. Khalaf

Department of Optics technique, AL-Farabi University College, Baghdad, Iraq

Bahaa Abdullah Lafttah Al-Rubaii

Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq


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How to Cite

Salih Ali A, Hazim Hamoode R, A. Khalaf Z, Abdullah Lafttah Al-Rubaii B. Predictive value of insulin marker before and after recovery of Grave’s disease patients. Biomedicine [Internet]. 2023 Aug. 30 [cited 2023 Oct. 4];43(4):1173-6. Available from:



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