Patterns of clinical and biochemical studies on elderly patients with anemia in the southern regions of Kyrgyzstan
Keywords:Anemia, iron deficiency anemia, vitamin B12-deficiency anemia, anemia of chronic disease
Introduction and Aim: Most studies indicate that between 10% and 45% of older people have anemia. The etiology is diverse and usually complicated. The aim of this study is to evaluate the clinical and hematological models of anemia in elderly residents of nursing homes in Kyrgyzstan's southern regions who are 60 years of age and older.
Materials and Methods: A total of 223 elderly persons, including 97 (43.5%) men and 126 (56.5%) women, participated in this study at nursing facilities in the southern areas of Kyrgyzstan. The elderly persons were 77.95.18 years old on average.
Results: 23.3% of the 223 older people in the study living in wards of nursing facilities in the southern areas of Kyrgyzstan were anemic. Iron deficiency anemia (IDA) (50%) was the most prevalent type of anemia, followed by vitamin B12 deficiency anemia (26.7%), and anemia of chronic disease (23.1%). Both blood ferritin and serum iron levels were considerably below normal, which is common for IDA. The value of vitamin B12 in the blood, which was within the usual limits (461.0–5.73 ng/l), was also revealed, indicating IDA.
Conclusion: Anemia affects quality of life and increases morbidity and mortality in elderly people.
Johnson-Wimbley, T. D., Graham, D. Y. Diagnosis and management of iron deficiency anemia in the 21st century. Therap Adv Gastroenterol. 2011;4(3):177-184.
Balasubramaniyam, K., Balakrishnan, G., Thalenjeri, P., Rao, V. A descriptive study of myriad risk factors in anemia of varied severity among reproductive female patients visiting a tertiary care setup in coastal Karnataka. Biomedicine. 2023; 43(02):706-712.
Allali, S., Brousse, V., Sacri, A. S., Chalumeau, M., de Montalembert, M. Anemia in children: prevalence, causes, diagnostic work-up, and long-term consequences. Expert Rev Hematol. 2017;10(11):1023-1028.
Walter, T. Effect of iron-deficiency anemia on cognitive skills and neuromaturation in infancy and childhood. Food Nutr Bull. 2003;24(4 Suppl): S104-S110.
Lukowski, A.F., Koss, M., Burden, M.J., Jonides, J., Nelson, C.A., Kaciroti, N., et al., Iron deficiency in infancy and neurocognitive functioning at 19 years: evidence of long-term deficits in executive function and recognition memory. Nutr Neurosci. 2010;13(2):54-70.
D. Rajkumar, Dineshkumar, J., Arunprasath, T. S. Anaemia in infants and young children- Risk factor analysis: Case control study. Biomedicine. 2022;42(1):169-172.
Yethindra, V. Role of GS-5734 (Remdesivir) in inhibiting SARS-CoV and MERS-CoV: The expected role of GS-5734 (Remdesivir) in COVID-19 (2019-nCoV) - VYTR hypothesis. Int J Res Pharm Sci. 2020;11:1-6.
Vityala, Y., Tagaev, T., Mamatov, S., Aidarov, Z., Harinath, P. Potential effects of itolizumab treatment on plasma interleukin-6 levels in patients with severe COVID-19. Indian J Pharmacol. 2021;53(3):246-247.
Yethindra, V., Tagaev, T. Decreased mortality among hospitalized coronavirus disease 2019 patients who underwent anticoagulant therapy with heparin. Indian J Pharmacol. 2020; 52(4):337-338.
Yethindra, V., Tagaev, T., Imankulova, A., Kaliev, M., Orozalieva, B., Niyazalieva, M., et al., Doxycycline inhibits SARS-CoV-2 replication in vitro. Biomedicine. 2022; 42(3): 612-615.
Kadyrova, A., Antipina, I., Kyrbasheva, I., Baudinov, I., Kulbaeva, B., Aitieva, U., et al., CT patterns and differential criteria for acute eosinophilic pneumonia and COVID-19 pneumonia. Clin Case Rep. 2021;9(10):e04890.
Vityala, Y., Kadyrova, A., Zhumabaeva, S., Bazarbaeva, A., Mamatov, S. Use of B-complex vitamins and olfactory training for treating COVID-19-related anosmia. Clin Case Rep. 2021;9(11): e05069.
Zhumabekova, A., Dzhanuzakova, N., Chynyeva, D., Mambetova, M., Niyazalieva, M., Vipin, et al., Neurological manifestations in pediatric patients with COVID-19: A case series. Biomedicine. 2023;42(6):1380-1382.
Vityala, Y., Mamytova, E., Turgumbaev, D., Kadyrova, A., Toktomametova, A., Zholdoshev, E., et al., Clinical features of acute ischemic stroke in moderately and severely ill patients with coronavirus disease 2019 (COVID-19). Biomedicine. 2021;41(2):397-400.
Guralnik, J. M., Eisenstaedt, R. S., Ferrucci, L., Klein, H. G, Woodman, R. C. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;104:2263-2268.
Stauder, R., Valent, P., Theurl, I. Anemia at older age: Etiologies, clinical implications, and management. Blood. 2018;131:505-514.
Bhasin, A., Rao, M.Y. Characteristics of anemia in elderly: A hospital based study in South India. Indian J Hematol Blood Transfus. 2011;27:26-32.
Sharma, D., Suri, V., Pannu, A.K., Attri, S.V., Varma, N., Kochhar, R., et al., Patterns of geriatric anemia: A hospital based observational study in North India. J Family Med Prim Care. 2019;8:976-980.
Bisht, N., Sofia, N. S. Prevalence and pattern of anemia in elderly A hospital based study. Int J Curr Res Med Sci. 2017; 3:27-35.
Juárez-Cedillo, T., Basurto-Acevedo, L., Vega-García, S., Manuel-Apolinar. L., Cruz-Tesoro, E., Rodríguez-Pérez, J. M., et al., Prevalence of anemia and its impact on the state of frailty in elderly people living in the community: SADEM study. Ann Hematol. 2014; 93(12): 2057-2062.
Le, C. H. The prevalence of anemia and moderate-severe anemia in the US population (NHANES 2003-2012). PloS one. 2016;11(11):e0166635.
Zakai, N. A., McClure, L. A., Prineas, R., Howard, G., McClellan, W., Holmes, C. E., et al., Correlates of anemia in American blacks and whites: the REGARDS renal ancillary study. Am J Epidemiol. 2009;169(3): 355-364.
Gaskell, H., Derry, S., Moore, R., McQuay, H. Prevalence of anaemia in older persons: systematic review. BMC. Geriatrics. 2008;8:1-7.
Sahin, S., Tasar, P. T., Simsek, H., Çicek, Z., Eskiizmirli, H., Aykar, F.S., et al., Prevalence of anemia and malnutrition and their association in elderly nursing home residents. Aging Clin Exp Res. 2016;28(5):857-862.
Zaninetti, C., Klersy, C., Scavariello, C., Bastia, R., Balduini, C. L., Invernizzi, R. Prevalence of anemia in hospitalized internal medicine patients: correlations with comorbidities and length of hospital stay. Eur J Intern Med. 2018;51:11-17.
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