Clinicopathological profile of invasive ductal breast carcinoma in a government tertiary care center in eastern India

Authors

  • Mrityunjay Pal
  • Saugata Ray
  • Priyanka Rani
  • Gautam Prakash
  • Raju Gupta

DOI:

https://doi.org/10.51248/.v40i4.329

Keywords:

Ductal breast carcinoma, ALN, LVE, mastectomy, estrogen receptors, progesterone receptors

Abstract

Introduction and Aim: There is an increasing incidence of breast cancer (BC) in our country. The study aimed to find out the demographic profile, clinical presentation, and management in patients treated for invasive ductal breast carcinoma (IDC) in a rural government teaching hospital and to study the association of sociodemographic factors with BC stage.

Materials and Methods: The study retrospectively analyzed 100 IDC females treated at Midnapore medical college, West Bengal, India from January 2017 to December 2019. The study included female patients of all ages diagnosed with IDC who had undergone surgery. Male BC, bilateral BC, other pathological types of BC were excluded.

Results: The mean age was 56.54±12.99 years. Sixty-seven cases were postmenopausal. Eighty-one cases were from rural areas. Seventy-three cases had education up to middle school. Eighty-six cases had a lower socioeconomic status. Ninety-eight cases had unilateral breast lump and only 2% had a nonpalpable breast lump. The left breast was more commonly involved. The mean tumour size was 4.33 cm. Ninety-eight cases underwent a modified radical mastectomy. Stage III was the most commonly observed BC and seen in 40 cases followed by stage II in 36 cases. Sixty-one cases had advanced BC. Liver metastasis was seen in 21cases. Sixty-nine cases had axillary node(ALN) positivity. Sixty-eight cases had lymphovascular emboli (LVE). High-grade tumour was seen in 77%. High-grade tumour was more common in young women. Seventy three cases of tumours were estrogen receptor-positive (ER+) while 66% progesterone receptor-positive (PR+). Eighteen cases were human epidermal growth factor 2 receptor-positive.

Conclusion: High incidence of advanced BC is found in rural areas due to a lack of awareness and health infrastructure.

Author Biographies

Mrityunjay Pal

Assistant Professor, Department of General Surgery, Midnapore Medical College, West Midnapore, 721 101, West Bengal, India

Saugata Ray

Associate Professor,Department of General Surgery, Midnapore Medical College, West Midnapore, 721 101, West Bengal, India

Priyanka Rani

Postgraduate student, Department of Obstetrics and Gynecology, Vardhaman Mahavir Medical College, New Delhi, 110 029 India

Gautam Prakash

Postgraduate student, Department of General Surgery, Midnapore Medical College, West Midnapore, 721 101, West Bengal, India

Raju Gupta

School of Medical Science and Technology, Indian Institute of Technology, Kharagpur, West Midnapore, 721 302, West Bengal, India

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Published

2021-01-01

How to Cite

1.
Pal M, Ray S, Rani P, Prakash G, Gupta R. Clinicopathological profile of invasive ductal breast carcinoma in a government tertiary care center in eastern India. Biomedicine [Internet]. 2021Jan.1 [cited 2021May14];40(4):502-6. Available from: https://biomedicineonline.org/index.php/home/article/view/329

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Original Research Articles