Role of Q-heterochromatin and thermal conductivity of the human body in the development of obesity


  • Stalbek Akhunbaev
  • Orozaly Uzakov
  • Yethindra Vityala



Q-heterochromatin, thermal conductivity, obesity, temperature gradient, chromosome


Introduction and Aim: Obesity, commonly known as a complex multifactorial disease, has emerged as a significant medical and societal issue in recent decades. The objective of this study is to assess if there is a significant impact of Q-heterochromatin (Q-HR) and thermal conductivity (k) in the body on the risk of obesity.


Methods: This prospective analytical cohort study included 300 individuals from both genders aged 35.24 4.21 years who do not have oncological, hormonal, or other forms of diseases that predispose to morbid obesity.


Results: In obese individuals, the temperature distribution in the peripheral and central parts of the body has a high level of variability relative to the control. In the main group, Q HR has a clear gradient from 0 to 2, and the average numerical parameter is 1.21 0.11, which is more than twice as low as in the control group (2.94 0.14). In obese individuals, the chromatin concentration decreased with increasing temperature gradient (X2 = -16.8; p0.001).


Conclusion: The level of Q-HR is considerably lower in obese people compared to the control group. When compared to the control, obese people had a higher k between the central and peripheral sections. The level of Q-HR and k were shown to be inversely correlated.

Author Biographies

Stalbek Akhunbaev

Administration of International Higher School of Medicine, Bishkek, Kyrgyzstan

Orozaly Uzakov

Administration of International Higher School of Medicine, Bishkek, Kyrgyzstan

Yethindra Vityala

Honorary International Faculty, AJ Research Centre, AJ Institute of Medical Sciences and Research Centre, Mangalore, Karnataka, India


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How to Cite

Akhunbaev S, Uzakov O, Vityala Y. Role of Q-heterochromatin and thermal conductivity of the human body in the development of obesity. Biomedicine [Internet]. 2023 Nov. 9 [cited 2023 Dec. 2];43(5):1546-9. Available from:



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