Effectiveness of nurse-led clinical interventions on knowledge, physiological and psychological outcomes, and symptom burden among patients undergoing hemodialysis -Part 1 pilot study


  • Shobha Kadabahalli Rajanna
  • Larissa Martha Sams




Chronic kidney disease, knowledge, physiological outcome, stress, coping, quality of life, symptom burden, hemodialysis


Introduction and Aim: The most popular treatment for treating severe and irreversible renal failure is hemodialysis. Even under the greatest circumstances, getting used to kidney failure's consequences and the time spent on dialysis may be challenging. In addition to the ‘lost time’, the patient could feel less energetic.. This pilot research aims to assess the efficacy of video-assisted teaching on selective nurse-led clinical interventions to improve knowledge, physiological and psychological outcomes and reduce the symptom burden among patients undergoing hemodialysis.


Materials and Methods: Forty hemodialysis patients were recruited and randomly allocated to intervention (n = 20) and control groups (n = 20) using an evaluative pre-test and post-test repeated measure study design with the control group. Patients in the intervention group received intervention in terms of Watching a video clip (40 minutes) - the video consist of disease condition, hemodialysis, dietary habits, fluid restriction, sleep hygiene, meditation, and yoga techniques, for two weeks after pre-test, later practice session, and group discussion along with Individualised teaching and counseling session, finally a regular weekly follow up at dialysis unit, while the control group received only routine care.


Results: In the intervention group there was a gradual increase in knowledge, coping and QoL (quality of life), reduction in stress and symptom burden, and physiological outcomes remain the same without much change. In the control group, they did not change the knowledge, physiological and psychological outcomes, and symptom burden in most of the patients. 


Conclusion:  For enhancing knowledge, physiological and psychological results, and symptom load, nurse-led clinical treatments are helpful, safe, essential, natural therapies that may be carried out under supervision both during hemodialysis and at home. Nurse-led clinical interventions integrated into routine care shall lead to improvements in patients’ life.

Author Biographies

Shobha Kadabahalli Rajanna

Adhichunchanagiri College of Nursing, B G nagara, “Karnataka and Ph.D. Scholar, Rajiv Gandhi University of Health Sciences, Karnataka, India

Larissa Martha Sams

Department of Medical-Surgical Nursing, Laxmi Memorial College of Nursing, Mangalore, Karnataka, India”


Ke, C., Liang, J., Liu, M.,Liu, S., Wang, C. Burden of chronic kidney disease and its risk-attributable burden in 137 low-and middle-income countries, 1990–2019: results from the global burden of disease study 2019, BMC Nephrology. 2022; 23:17, https://doi.org/10.1186/s12882-021-02597-3 2

www.thelancet.com Vol 395 February 29, 2020.

D’Souza, B., Prabhu, R.A., Unnikrishnan, B., Ballal, S., Kamath, A. Effect of educational intervention on knowledge and level of adherence among hemodialysis patients – A randomized control trial. research square: https://doi.org/ 10.21203/rs.3.rs-1194596/v1

Maheshkumar, K., Jayakumar, M., Silambanan, S., Devanand, V. Novel biomarkers of inflammation for endothelial dysfunction in chronic kidney disease patients. Biomedicine. 2022 Mar 5;42(1):177-1780.

Hanifa, B.F., Musaevich, K.M., Tagaev, T., Vityala, Y. Characteristics of need and availability of renal replacement therapy for patients with chronic kidney disease in Azerbaijan. Biomedicine. 2023 Mar 28;43(01):353-357.

Zhianfar, L., Nadrian, H., Jafarabadi, M.A., Espahbodi, F., Shaghaghi, A. Effectiveness of a multifaceted educational intervention to enhance therapeutic regimen adherence and quality of life amongst Iranian hemodialysis patients: A randomized controlled trial (MEITRA Study). Journal of Multidisciplinary Healthcare.2020;13:361.

Arad, M., Goli, R., Parizad, N., Vahabzadeh, D., Baghaei,R. Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial: BMC Nephrology. 2021; 22:119.

6.You, A.S., Kalantar, S.S., Norris, K.C., Peralta, R. A., Narasaki, Y., Fischman, R., et al., Dialysis symptom index burden and symptom clusters in a prospective cohort of dialysis patients. Journal of Nephrology. https://doi.org/10.1007/s40620-022-01313-0

Floria, I., Kontele, I., Grammatikopoulou, M.G., Theodoros N. Sergentanis, Tonia Vassilakou. Quality of Life of Hemodialysis Patients in Greece:Associations with Socio-Economic, Anthropometric and Nutritional Factors, Int. J. Environ. Res. Public Health. 2022; 19:15389.

Bhalendu, S., Vaishnav, Hirapara, J.J., Shah, M.K. Study of effect of guided meditation on quality of life in patients of end stage renal disease (ESRD) on maintenance hemodialysis – a randomized controlled trial. BMC Complementary Medicine and Therapies. 2022; 22:238.




How to Cite

Kadabahalli Rajanna S, Martha Sams L. Effectiveness of nurse-led clinical interventions on knowledge, physiological and psychological outcomes, and symptom burden among patients undergoing hemodialysis -Part 1 pilot study. Biomedicine [Internet]. 2023 Nov. 9 [cited 2023 Dec. 2];43(5):1562-7. Available from: https://biomedicineonline.org/index.php/home/article/view/3649



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