Effects of hookah smoking on liver functions, lipid profile, and adult blood count


  • Muna Yaseen Department of Basic Science, College of Dentistry, University of Anbar, Anbar, Iraq
  • Sami Alkubaisy Desert Studies Center, College of Applied Science, University of Anbar, Anbar, Iraq
  • Marwan Mahmood Saleh Department of Biophysics, College of Applied Science, University of Anbar, Anbar, Iraq




Smoker, lipid profile, blood, shisha


Introduction and Aim: Smoking is the most common habit and the largest health risk among people who have an impact on the human body. The goal of our study was to examine the effects of hookah (Shisha) on the liver, lipid profile, and blood content in adult smokers to adult non-smokers.


Materials and Methods: A total of 50 men between the ages of 30 and 60 years took part in the study. These samples were divided into two groups: 30 smokers and 20 non-smokers. Every male is subjected to a complete medical history survey as well as frequent tests to rule out any underlying illnesses or diseases. Blood samples were taken in quantities of 10 mL to examine the blood.  Blood samples were placed on the red roof when blood samples were used with anticoagulant factor. The identification of biological parameters was done using enzyme methods and a Random kit.


Results: The results showed that Hb, PCV, WBC, ESR, platelets, and RBC were all elevated, whereas ALP and transaminase enzymes were not. Although not significantly, TC and TG increased the lipid profile findings. Our analysis yielded a wide range of outcomes. Various factors could be to blame for these disparities.


Conclusion: We describe how future research will focus on the relationship between organ functions and their working tests for smoking effects based on our findings. Age, sex, nutrition, and hereditary behavior must all be included in future studies.


Maziak, W. The waterpipe: an emerging global risk for cancer. Cancer Epidemiol. 2013; 37: 1-4.

Nakkash, R., Khalil, J. Health warning labelling practices on narghile (shisha, hookah) waterpipe tobacco products and related accessories. Tob Control. 2010; 19 (3): 235-239.

Bou Fakhreddine, H. M., Kanj, A. N., Kanj, N. A. The growing epidemic of water pipe smoking: health effects and future needs. Respir Med. 2014; 108(9): 1241-1253.

Jukema, J. B., Bagnasco, D. E., Jukema, R. A. Waterpipe smoking: not necessarily less hazardous than cigarette smoking: possible consequences for (cardiovascular) disease. Neth Heart J. 2014; 22(3): 91-99.

Fiala, S. C., Morris, D. S., Pawlak, R. L. Measuring indoor air quality of hookah lounges. Am J Public Health. 2012; 102: 2043-2045.

Fortmann A. L., Romero R. A., Sklar, M., Pham, V., Zakarian, J., Quintana, P. J., et al., Residual tobacco smoke in used cars: Futile efforts and persistent pollutants. Nicotine Tob Res. 2010; 12: 1029-1036.

Chaouachi, K. Hookah (Shisha, Narghile) Smoking and Environmental Tobacco Smoke (ETS). A Critical Review of the Relevant Literature and the Public Health Consequences. 2009; 798-843. https://doi.org/10.3390/ijerph6020798.

Sajid, K. M., Chaouachi, K. & Mahmood, R. Hookah smoking and cancer: carcinoembryonic antigen (CEA) levels in exclusive/ever hookah smokers. Harm Reduct J. 2008; 5(19): 1-8. https://doi.org/10.1186/1477-7517-5-19

SAS Institute INC. (2002). SAS/STAT Users Guide: Version 9.1 (Cary, NC, SAS Institute, Inc.). 10-Duncan, D.B. Multiple range and multiple F-tests. Biometrics. 1955; 11: 1-42.

Shah, B. K., Nepal, A. K., Agrawal, M., Sinha, A. K. The effects of cigarette smoking on hemoglobin levels compared between smokers and non-smokers. Sunsari Tech. Coll. J. 2012; 1(1): 1-3.

Law, M.R., Wald, N.J. Environmental tobacco smoke and ischemic heart disease. Progress in Cardiovascular Diseases. 2003; 46(1): 31-38.

Hioki, H., Aoki, N., Kawano, K., Homori, M., Hasumura, Y., Yasumura, T. et al., Acute effects of cigarette smoking on platelet-dependent thrombin generation. Eur Heart J. 2001; 22(1): 56-61.

Zalokar, J. B., Richard, J. L., Claude, J. R. Leukocyte count, smoking, and myocardial infarction. N Engl J Med. 1981; 304(8): 465-468.

Chang, E., Forsberg, E. C., Wu, J. Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? Vasc Med. 2010; 15(5): 375-385.

Alzurfi, S. K., Al-Gburi, J. B., Al- Graiti, T. A. Effects of hookah smoking on blood contents and some organ functions of men body, J Phys: Conf Ser. 2019; 1234: 012077. doi:10.1088/1742-6596/1234/1/012077.

Khan, M. I., Bukhari, M. H., Akhtar, M. S., Brar, S. Effect of smoking on red blood cells count, hemoglobin concentration and red cell indices. P J M H S. 2014; 8(2): 361-364.

Sharma, A., Yadav, B., Pathak, R., Singh, A. K., Hussein, M., Singh, S. Effect of smoking on erythrocyte sedimentation rate, bleeding time and clotting time of young adults. Natl. J. Med. Allied Sci. 2014; 3(1): 19-23.

Jang, E. S., Heong, S., Hwang, S., Kim, H., Ahn, S., Lee, J., et al., Effects of coffee, smoking and alcohol on liver function tests: a comprehensive cross-sectional study. BMC Gastroenterology.2012; 12(1): 145.

Lee, L. K., Paul, C. Y. C, Kam, C. W., Jagmohni, K. Smoking among Secondary School Students in Negeri Sembilan, Malaysia. Asia Pac J Public Health. 2005; 17(2): 130-136.

Chan-Yeung, M., Ferreira, P., Frohlich, J., Tan, F. The Effects of Age, Smoking, and Alcohol on Routine Laboratory Tests. Am J Clin Pathol. 1981; 75(3): 320-326.

Zabala, V., Tong, M., Yu, R., Ramirez, T., Yalcin, E. B., Balbo, S., et al., Potential contributions of the tobacco nicotine-derived nitrosamine ketone (NNK) in the pathogenesis of steatohepatitis in a chronic plus binge rat model of alcoholic liver disease. Alcohol Alcohol. 2015; 50(2): 118-131.

Fujimoto, H., Tsuji, H., Okubo, C., Fukuda, I., Nishino, T., Lee, K.M., et al., Biological responses in rats exposed to mainstream smoke from a heated cigarette compared to a conventional reference cigarette. Inhal Toxicol. 2015; 27(4): 224 -236.

Wisniewska, E., Dylik, A., Kulza, M., Florek, E., Piekoszewski, W., Senczuk-Przybylowska, M., et al., Exposure to ethanol and tobacco smoke in relation to level of PCNA antigen expression in pancreatic and hepatic rat cells. Pharmacol Rep. 2013; 65(4): 914-926.

Frati, A. C., Iniestra, F., Ariza, C. R. Acute effect of cigarette smoking on glucose tolerance and other cardiovascular risk factors. Diabetes care. 1996; 19(2): 112-118.

Alkubaisy, S., Yaseen, M., Mahmood, M., The effects of cinnamon powder on glucose and lipoprotein profile levels in patients with type 2 diabetes mellitus in Ramadi city, Al-Anbar province, Iraq. International Medical Journal. 2019; 26(5): pp. 373-375.




How to Cite

Yaseen M, Alkubaisy S, Saleh MM. Effects of hookah smoking on liver functions, lipid profile, and adult blood count. Biomedicine [Internet]. 2021Dec.31 [cited 2022Jul.2];41(4):763-7. Available from: https://biomedicineonline.org/index.php/home/article/view/891



Original Research Articles