Effect of vitamin D supplementation on fetal growth and development in pregnant women


  • Srilekha V. Department of Physiology, SVS Medical College, Mahabubnagar, 509001 Telangana, India
  • B. Vijayalakshmi Department of Physiology, Saveetha Medical College, Saveetha University, Chennai, Tamil Nadu, India
  • I. Yogananda Reddy Department of Physiology, ESI Medical College, Sanathnagar, Hyderabad, Telangana, India
  • Nayiema Fathima Department of Gynecology, SVS Medical College, Mahabubnagar, Telangana, India




Fetal growth, bicephalic diameter, cholecalciferol, hypocalcemia, fetal growth restriction


Introduction and Aim:  Fetal growth is a dynamic process that must be monitored in pregnant women to reduce the long-term consequences of fetal anomalies and post-natal effects on their life. The current study was aimed to find out the effectiveness and association of vitamin D on fetal growth during the prenatal period.


Materials and Methods: It was a randomized control trial undertaken in 100 pregnant women who were allocated randomly into two groups based on calcemic state. After giving 6000 IU of vitamin D intervention the fetal growth was measured at the end of 3 months and the variables were obtained before and after the intervention.


Results: The mean difference of fetal weight between groups was 77g was significantly increased to 277g (p<0.01) after 3 months. The mean difference of femur length before intervention was 0.95mm (p-0.18) significantly increased to 3.03mm (p<0.01). Further, the mean biparietal diameter difference was 0.13mm (p-0.92) was substantially increased to 4.77mm(p<0.01).


Conclusion: The current study suggests that the fetal growth variables were significantly increased in post-intervention phases which can be attributed to vitamin D. It has an immense effect on fetal growth which can be supplemented during different trimesters to enhance fetal development.


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How to Cite

V. S, Vijayalakshmi B, Reddy IY, Fathima N. Effect of vitamin D supplementation on fetal growth and development in pregnant women. Biomedicine [Internet]. 2021Dec.31 [cited 2022Jan.20];41(4):821-4. Available from: https://biomedicineonline.org/index.php/home/article/view/926



Original Research Articles