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Biomedicine

Volume: 42 Issue: 4

  • Open Access
  • Short communications/brief reports

Analysis of smear patterns in tubercular lymphadenitis by fine needle aspiration cytology in a tertiary care hospital

Amina Mukhtar1, Crysle Saldanha2

2Department of Pathology, 1Father Muller Medical College, Mangalore, 575002, Karnataka, India

Corresponding author: Crysle Saldanha. Email: [email protected]

Year: 2022, Page: 823-827, Doi: https://doi.org/10.51248/.v42i4.1426

Abstract

Introduction and Aim: India accounts for the highest number of extrapulmonary tuberculosis (EPTB), frequently manifested as lymphadenitis. Our study is designed to evaluate cytological patterns of tubercular lymphadenitis in FNAC, a rapid diagnostic procedure among patients in a tertiary care hospital presenting with lymphadenopathy.
Materials and Methods: A total of 193 patients were detected with tubercular lymphadenitis in a 3-year cross-sectional study. Chi-square test was done to analyze the patterns of tubercular lymphadenitis in FNAC and its association with Acid fast bacilli staining.
Results: The highest frequency of tubercular lymphadenitis was observed in cervical lymph nodes 125/193 cases (64.77%). Pattern B (epithelioid granuloma with necrosis) 94 cases (48.7%) constituted the predominant pattern. AFB positive smears were graded as follows, grade 1 +: 28.6%, grade 2 +:47.6%, grade 3+: 23.8%. Grade 3 AFB positivity was observed among HIV (four cases) positive patients.
Conclusion: FNAC is a minimally invasive procedure in patients with Tuberculous Lymphadenitis, an extra pulmonary manifestation of Mycobacterial tuberculosis.

Keywords: Cytology; tuberculosis; HIV; ZN staining.

Cite this article

Amina Mukhtar, Crysle Saldanha. Analysis of smear patterns in tubercular lymphadenitis by fine needle aspiration
cytology in a tertiary care hospital. Biomedicine: 2022; 42(4): 823-827

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