Biomedicine

Abstract

Stress during pregnancy is a causative factor for inducing the materno-fetal morbidity and mortality. Efforts to
prevent or treat pregnancy stress are not progressive. Delivery remains the ultimate treatment for pregnancy
stress associated complications. The current review deals with oxidant/antioxidant status, stress-inducible factor
and effect of various antioxidant therapies during pregnancy in particular context to gestational hypertension,
gestational diabetes mellitus, preeclampsia, and Ureaplasmaurealyticum infection. Different alternative drugs
are employed to increase the endogenous antioxidant level. The possible positive effect on administration
of mint-black tea, black tea and green tea in managing the oxidative/nitrative stress in pregnancy-associated
complications are discussed. The review suggests the protective effect of mint-tea and tea extracts against
placental hypoxia-induced oxidative/nitrative stress. Since treatment of the disease with modern medicine is
often associated with severe side effects that may affect both mother and fetus,tea and mint-tea extracts with
natural medicinal properties can be recommended as an alternative herbal remedy for pregnancy-associated
complications to reduce oxidative/nitrative stress and enhance live fetal delivery.