Biomedicine

Abstract

Introduction and Aim: The bone marrow is responsible for the supply of oxygen and restores the cells that form the blood of a tissue. The objective is to study the cadaveric bone marrow cells from dead children of different regions of Kyrgyzstan.
Materials and Methods: Bone marrow examination was performed on 38 cadavers (Bishkek–11, Kara-Balta–9, Cholpon-Ata–10, and Naryn–8) of children dead due to causes unrelated to immunodeficiency. The cadaveric bone marrow cells from dead children were collected within a day after death.
Results: Studies of cadaveric bone marrow cells from dead children in Kara-Balta showed an increase in basophils, eosinophils, lymphocytes, leukoerythroblastosis, and a decrease in myelocytes. Erythroid growth according to the normoblast hematopoiesis was slightly decreased. Megakaryocytes were single or absent (no function) and contained small number of platelets.
Conclusion: Cadaveric bone marrow cells taken from dead children who lived near the uranium tailings dump of Kara-Balta, demonstrated an anomaly with the hematopoietic function of the bone marrow, the state of the stroma, the ratio of hematopoietic and adipose tissue, cellular composition, different pathological processes as indicated by myelocytes in comparison to dead children from other regions (Bishkek, Cholpon-Ata, and Naryn).