Volume: 43 Issue: 3
Year: 2023, Page: 1076-1079, Doi: https://doi.org/10.51248/.v43i3.2099
Herpes simplex virus (HSV) is a double-stranded DNA virus that exists in two forms- HSV 1 and HSV 2. Oral herpetic lesions are typically caused by HSV-1. In the oral cavity, they are known to cause painful lesions that most commonly involve gingiva, palate, and buccal mucosa. Since it is a contagious infection and has the potential to cause complications in the host, timely diagnosis and management are important. Therefore, dental professionals must be aware of clinical presentation and appropriate diagnostic and management measures. The following case report discusses a case of Herpes Simplex Virus in a 33-year-old, systemically healthy female patient, who reported to the dental OPD with oral symptoms. The clinical features, investigations, diagnosis, and management of the condition have been elaborated in the review.
Keywords: Herpes; herpes simplex virus; oral herpetic lesion.
1. Fatahzadeh, M., Schwartz, R.A. Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. Journal of the American Academy of Dermatology. 2007;57(5):737-763.
2. Sainz, Jr B., Halford, W.P. Alpha/Beta interferon and gamma interferon synergize to inhibit the replication of herpes simplex virus type 1. Journal of Virology. 2002; 76(22):11541-11550.
3. Batterson, W.I., Roizman, B.E. Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes. Journal of Virology. 1983 May;46(2):371-377.
4. Clarkson, E., Mashkoor, F., Abdulateef, S. Oral viral infections: diagnosis and management. Dental Clinics. 2017; 61(2):351-363.
5. Santosh, A.B., Muddana, K. Viral infections of oral cavity. Journal of Family Medicine and Primary Care. 2020; 9(1):36.
6. Divya, G., Asokan, G.S., Tamilarasi, U., Anand, V., Balaji, N. Herpetic Ulcer: A case report and a review literature. Biomedical & Pharmacology Journal. 2015 Oct 1;8:495.
7. Frisch, S., Guo, A.M. Diagnostic methods and management strategies of herpes simplex and herpes zoster infections. Clinics in Geriatric Medicine. 2013; 29(2):501-526.
8. McCullough, M.J., Savage, N.W. Oral viral infections and the therapeutic use of antiviral agents in dentistry. Australian Dental Journal. 2005;50:S31-S35.
9. Huber, M.A. Herpes simplex type-1 virus infection. Quintessence International. 2003; 34(6).
10. Ramchandani, M., Kong, M., Tronstein, E., Selke, S., Mikhaylova, A., Magaret, A., et al., Herpes simplex virus type 1 shedding in tears, and nasal and oral mucosa of healthy adults. Sexually Transmitted Diseases. 2016;43(12):756.
11. Kimberlin, D.W. Management of HSV encephalitis in adults and neonates: diagnosis, prognosis and treatment. Herpes: the journal of the IHMF. 2007;14(1):11-16.
12. Kłysik, K., Pietraszek, A., Karewicz, A., Nowakowska, M. Acyclovir in the treatment of herpes viruses–a review. Current Medicinal Chemistry. 2020; 27(24):4118-4137.
Mamatha Shetty, Deepa Sara John, Surabhi Durgapal, Urvashi Shetty. Herpes simplex virus: A case report and review of literature. Biomedicine: 2023; 43(3): 1076-1079