Volume: 44 Issue: 3
Year: 2024, Page: 310-316, Doi: https://doi.org/10.51248/v44i3.29
Introduction and Aim: In India, cardiovascular diseases (CVD) contribute to a major cause of morbidity and mortality. Consuming more or significant quantity of fish has been linked to a lower the vulnerability of CVD. This is due to fish oils contains long-chain n-3 polyunsaturated fatty acids (PUFA), like docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Frequent intake of these fatty acids has demonstrated to reduce the vulnerability of endothelial dysfunction, inflammation, arrhythmias, heart failure, myocardial infarction, and sudden death. The protective advantages of a diet high in fish seems to be at odds with the oxidation susceptibility of polyunsaturated fats (PUFAs). Therefore, the goal of the research was to assess the lipid profile, cardiac markers, and state of lipid peroxidation in adult females who regularly eat substantial quantities of fish. Materials and Methods: Measurements were made of the following in healthy female individuals: total cholesterol (TC), HDL-cholesterol (HDL-C), triglycerides (TG), high sensitive C-reactive protein (hs-CRP), lipoprotein (a) [Lp(a)], malondialdehyde (MDA), and antioxidant activity (AOA). The atherogenic indices TC/ HDL-C, LDL-C/HDL-C and non- HDL-C/ HDL-C were determined. Applying Student's "t" test, the parameters of the two groups were compared. Results: Among female individuals who consumed fish, HDL-C was the only cardiac marker that increased while all other cardiac markers and the lipid profile decreased. The atherogenic indices of fish eaters showed considerable declines, whereas the oxidant status between the study groups did not vary significantly (p>0.05). Conclusion: The outcome of this study reveals that, without influencing an individual's oxidation status, a frequent consumption of fish reduces the lipid profile and cardiac markers.
Keywords: Fish eaters; vegetarians; lipid profile; hs-CRP; Lp(a); cardiovascular disease.
Asha Prabhu, Kedilaya, H.P., Raghavendra L. S. Hallur, Manjula Shantaram. Impact of fish on biochemical indicators: A comparative analysis among female subjects of fish eaters and vegans. Biomedicine: 2024, 44(3): 310-316