Biomedicine

This brief review explores the integration of translational research, protein profiling, and artificial intelligence (AI) in predicting COVID-19 severity and optimizing recovery, focusing on Heat Shock Proteins (HSPs) as critical biomarkers. Translational research translates molecular findings i…

Introduction and Aim: The use of intrathecal adjuvants extends the block's duration, resulting in a higher success rate and increased patient satisfaction. Additionally, it offers acceptable pain control. Dexmedetomidine may be utilized as an epidural adjuvant with local anesthetic sparing p…

Understanding the molecular underpinnings of colorectal cancer (CRC) is crucial for advancing its diagnosis and treatment. This review aims to provide a comprehensive overview of recent developments in CRC research, with a focus on biomarkers and nanotechnology-based approaches. The objectives a…

The complex terrain of gender differences in cardiovascular disease (CVD) diagnosis and treatment is explored in this short review article. Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, accounting for an estimated 17.9 million deaths each year, repr…

Around the globe, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) pose significant health risks, with a shortage of effective therapeutic options. The potential impact of vitamin E in controlling these conditions has garnered substantial attention. This review …

Frailty has emerged as a critical factor in healthcare, particularly within critical illness, cardiology, and cardiac surgery. This review examines the assessment methods and practical application of frailty measurements within the Indian healthcare system. By analyzing existing literature and r…

Introduction and Aim: Mycotoxins are toxic by-products of fungi that can appear in bakery foods including bread, cake, and biscuits, among others. Mycotoxins generated by filamentous fungus (moulds) have a severe influence on the sustainability of food sources and cause significant economic loss…

In order to control diabetes mellitus, this review article offers a thorough comparison and analysis of once-weekly tirzepatide and once-daily insulin degludec. The review looks at their pharmacokinetics, dosage schedules, and effects on glycemic control and assesses the effectiveness, safety, a…

Introduction and Aim: Road traffic accidents (RTAs) are becoming more common owing to factors such as increased vehicle usage, daily changes, traffic law violations, anarchic systems, and risky driving practices. Thoracoabdominal injuries are a major cause of mortality in fatal traffic accidents…

Introduction and Aim: The compression of the cervical nerve roots causes cervical radiculopathy. Pain, motor impairments, sensory deficits, decreased or absent reflexes, or any combination are all clinical characteristics. Non-operative management includes intermittent cervical traction, transcu…

Background: In the dynamic field of medical education, assessment methods have evolved significantly. One notable shift is the transition from traditional paper-based spotter tests to digital formats, primarily facilitated by PowerPoint presentations. Traditionally, spotter tests involved identi…

Introduction and aim Breast cancer is a leading cause of death in Mizoram, Northeast India. Germline mutations in breast cancer patients have been associated with factors such as age, pathology, and ethnicity. This study aimed to screen for germline mutations in select marker genes in a high-ris…

Introduction: Adult-onset hypogonadism (AOH) is a disorder due to low serum testosterone levels and is seen in 50% of obese and diabetic males. In Obesity, excess adipose tissue converts Testosterone to estrogen thereby effectively lowering levels of testosterone in men. Obesity causes a reducti…

Introduction and Aim: In India, cardiovascular diseases (CVD) contribute to a major cause of morbidity and mortality. Consuming more or significant quantity of fish has been linked to a lower the vulnerability of CVD. This is due to fish oils contains long-chain n-3 polyunsaturated fatty acids (…

Introduction and Aim: The hypolipidemic activity, antioxidant activity and tissue fatty acid composition of high purity phytosterols (PS) obtained from rice bran oil deodorizer distillate (RBO DOD) was evaluated in free and esterified form. The phytosterol esters of ALA (PSE) were prepared by es…