Due to transition in the journal platform, the previously submitted articles, which are under process can be re-submitted here for quick process, kindly co-operate

Biomedicine

Volume: 44 Issue: 1

  • Open Access
  • Original Article

A comparative study of simple reaction time in PCOS and non-PCOS patients and its relation with BMI

 

 Preeti K.1, Priya S.A.1, Arun Gopi2, Kancherla Narasimha Abhinav Kaushal

 

1Department of Physiology, 2Department of Community Medicine, JSS Medical College, S. S. Nagar, Bannimantap, Mysuru 570015, Karnataka, India 

3Department of Pharmacology, Sri Devaraj Urs Medical College, Tamaka, Kolar, 563101, Karnataka, India 

 

 Corresponding author: Priya S.A. Email: [email protected] 

Year: 2024, Page: 151-153, Doi: https://doi.org/10.51248/.v44i1.4052

Received: Jan. 11, 2024 Accepted: Feb. 21, 2024 Published: May 1, 2024

Abstract

 

Introduction and Aim: Polycystic ovarian syndrome (PCOS) is a hormonal disorder of the female reproductive system causing infertility, an irregular menstrual cycle, and hormonal imbalance characterized by hyperandrogenism. Reaction to any stimulus is a voluntary response that measures the speed of response of a person. There is gender variation in reaction time, hence there is a need for evaluation of reaction time in PCOS. Thus, auditory and visual reaction time may be affected in the women with polycystic ovaries. The aim of the study was to compare ART and VRT in PCOS and non-PCOS Individuals and to correlate ART and VRT with BMI in PCOS individuals. 

Materials and Methods: Age-matched 25 normal and 25 PCOS were subjected to ART and VRT and recordings were obtained. The anthropological parameters like height, weight, and BMI were computed. The results were analyzed using a t-test and Pearson’s correlation test using SPSS software. 

Results: The auditory reaction time showed significant (p<0.001) increase in PCOS 0.318±0.0388 than non-PCOS individuals 0.239±0.0629. There was positive correlation (r=0.491, p<0.05) of BMI with visual reaction time in PCOS individuals. 

Conclusion: Since there is an increase in reaction time and a positive relation with BMI we can say that there is a decline in cognition in PCOS individuals probably due to hormonal changes and obesity. 

Keywords: Auditory reaction time; BMI; hyperandrogenism; PCOS; visual reaction time.

References

 

  1. Natelie Shaw, Robert Rosefield. https://www.uptodate.com/ contents/definition-clinical-features-and-differential-diagnosis-of-polycystic-ovary-syndrome-in-adolescents 
  2. Jacob, P. C., Marcelle, I. C. Current guidelines for diagnosing PCOS. Diagnostics (Basel). 2023;13(6):1113. 
  3. Barberi, R.L., Ehrmann, D.A. Clinical manifestations of polycystic ovary syndrome in adults. https://www.uptodate.com/contents/clinical-manifestations-of-polycystic-ovary-syndrome-in-adults 
  4. Min, M., Xiangyan, R., Alfred, O.M. Adavanced therapy of overweight or obese polycystic ovary syndrome:A prospective study. Global Health Journal. 2022;6(2):75-79 

  5. Cournot M., Marquie J. C., Ansiau D., Martinaud C., Fonds H., Ferrieres J., et al. Relation between body mass index and cognitive function in healthy middle-aged men and women. Neurology, 2006;67:1208-1214. 

  6. Gustafson, D., Lissner, L., Bengtsson,C., Bjorkelund, C., Skoog, I. A 24-year follow-up of body mass index and cerebral atrophy. Neurology, 2004;63:1876-1881. 

  7.  Pannacciulli, N., Parigi, A. D., Chen, K., Le, D.S., Reiman, E. M., Tataranni, P. A. Brain abnormalities in human obesity: a voxel-based morphometric study. Neuroimage, 2006;31:1419-1425.

  8. Hollinrake, E., Abreu, A., Maifeld, M.,Van,V. B., Dokras, A. J. Increased risk of depressive disorders in women with polycystic ovary syndrome. Fertility and Sterility. 2007;87: 1369-1376. 

  9. Weiner, C.L., Primeau, M., Ehrmann, D.A. Androgens and mood dysfunction in women: comparison of women with polycystic ovarian syndrome to healthy controls. Psychosom Med. 2004;66:356-362. 

  10. Barber, T.M., McCarthy, M.I., Wass, J.A., Franks, S. Obesity and polycystic ovary syndrome. Clin Endocrinol (Oxf). 2006; 65(2):137-145. 

  11.  Lim, S. S., Davies, M. J., Norman, R. J., Moran, L.J. Overweight, obesity and central obesity in women with polycystic ovary syndrome: A systematic review and meta-analysis. Hum Reprod Update. 2012;18(6): 618-637.

  12. Dunaif, A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev. 1997;18:774-800.

  13. Mohlig, M., Jurgens, A., Spranger, J., Hoffmann, K., Schlosser, H.W., Weickert, O.M. et al., The androgen receptor CAG repeat modifies the impact of testosterone on insulin resistance in women with polycystic ovary syndrome. Eur J Endocrinol. 2006;155:127-130. 

  14. Barber, T.M., Hanson, P., Weickert, M.O., Franks, S. Obesity and polycystic ovary syndrome: Implications for pathogenesis and novel management strategies. Clin Med Insights Reprod Health. 2019; 13:1179558119874042. 

  15. Mayouri, S., Kate, E., Katie, D., Anna, F., Christopher, F., Richard, J.P. Free testosterone is related to aspects of cognitive function in women with and without polycystic ovary syndrome Arch Womens Ment Health. 2022;25(1):87-94. 

  16. Barnard, A.H. Balen, D. Ferriday., Tiplady, B., Dye, L. Cognitive functioning in polycystic ovary syndrome. Psychoneuroendocrinology. 2007;32(8-10): 906-991. 

  17. Misra, N., Mahajan, K.K., Maini, B.K. Comparative study of visual and auditory reaction time of hands and feet in males and females. Indian J Physiol Pharmacol. 1985;29:213-218. 

  18. Nikam, L.H., Gadkari, J.V. Effect of age, gender, and body mass index on visual and auditory reaction times in the Indian population. Indian J Physiol Pharmacol. 2012;56:94-99. 

  19. O’Connor, D.B., Archer, J., Hair, W.M., Wu, F.C. Activational effects of testosterone on cognitive function in men. Neuropsychologia 2001;.39(13):1385-1394. 

  20. Wong, R.H., Scholey, A., Howe, P.R. Assessing premorbid cognitive ability in adults with type 2 diabetes mellitus- A review with implications for future intervention studies. Curr Diab Rep. 2014;14(11):547-547. 

  21.  Biessels, G.J., Staekenborg, S., Brunner, E., Brayne,C., Scheltens, P. Risk of dementia in diabetes mellitus: A systematic review. Lancet Neurol. 2006;5(1):64-74. 

Cite this article

  

Preeti K, Priya S.A, Arun Gopi, Kancherla Narasimha Abhinav Kaushal3 A comparative study of simple reaction time in PCOS and non-PCOS patients and its relation with BMI. Biomedicine: 2024; 44(1): 151-153 

  

 

Views
438
Downloads
61
Citations